Course Syllabus

Course Syllabus:

  • Introduction
    • Understanding the (scope of the) impact of microbiome as a complex ecosystem on nature and human health specificaly.
    • Components of the microbiome - microbes, fungus, archeae , virome
    • Microorganisms characterization methods - history and contemporary
  • Sequencing technology
    • Classic Sangar sequencing
    • Pyrosequencing
    • Illumina Miseq
    • Future technologies (nanopores, etc)
  • Omics Data analysis

    • 16S rRNA gene sequencing

      • Multidimensional scaling / dimension reduction
    • Metagenomics

    • Meta-transcriptomic

    • Metabolomic

  • The Human Microbiome project (HMP) and (iHMP)

  • High-Performance Computing / Environment

    • HPC

    • Qiita

    • Galaxy cluster

  • Frontier topics in the research of the microbiome (too similar to aim I of introduction?)

    • Where do we use these technologies, what do we like to find?
    • Leading fields of microbiome research in human health:
    • Saving ancesteral microbiome from extinction
    • Restoration of gut microbial ecology by fecal transplantation
    • Age, Obesity
    • Autoimmune diseases (like T1D) and food allergies
    • Pregnanncy \ Embryonic development
  • The future of the microbiome research

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